Applying Systemic Project Management Approaches for the UK National Health Service

This paper sets out some observations arising from on-going research into the use of systemic methods in the planning of complex projects within the National Health Service (NHS) in Staffordshire and Shropshire in the UK. This brief paper sets out the main reasons for the application of systemic approaches, the nature of the methodologies put in place and some of the outcomes and reflections of those involved in the various workshops. Whilst not attempting to be definitive in our conclusions, the authors believe that the results of the application of systemic methods by Health and Care professionals show a range of strengths going forward

Modellbetriebsplanung - Investitionsbedarf in der Ökosauenhaltung

In der ökologischen Ferkelerzeugung werden derzeit unterschiedliche Konzepte für Haltungsverfahren und Stallgebäude verwirklicht. Um einheitliche Aussagen zum Investitionsbedarf zu erhalten, wurde auf der Grundlage von ausgewählten Betrieben sowie der im Projekt gewonnenen Erkenntnisse, insbesondere zur Klimagestaltung des Abferkelbereichs, ein Modellbetrieb für 168 Sauen mit Ferkelaufzucht gemäß EG-Öko-Verordnung (EG) Nr.889/2008 in verschiedenen baulichen und funktionalen Varianten erarbeitet. Die Modellplanung lässt sich in zwei Grundmodelle einteilen, die sich durch die Anordnung der Abferkel- und Deck-/ Wartebereiche unterscheiden. MODELL I besteht aus mehrhäusigen Anlagen, bei denen sich die Stallabteile aller Produktionsbereiche in separaten Gebäuden befinden. Mit MODELL II liegt eine Kompaktbauweise vor. Hier wurden die Bereiche Abferkeln und Decken/ Warten in einen gemeinsamen Gebäudekomplex zusammengefasst. Die Ferkelaufzucht befindet sich bei beiden Modellvarianten in separaten Gebäuden. Der Investitionsbedarf der Stallmodelle wurde gemäß DIN 276 „Kosten im Hochbau“ über eine eigene Kostendatenbank sowie über Firmenangebote ermittelt. Der Investitionsbedarf je Sauenplatz beträgt bei reiner Fremdleistung ca. 7.300 bis ca. 7.650 €/netto

A Review of Psychosocial Risk Factors for Pediatric Atopy

Pediatric atopy is increasing in prevalence and creates a significant financial and quality of life burden for children and families (e.g., frequent clinic visits, academic, and social challenges). Thus, it is important to understand modifiable risk factors related to disease onset or exacerbation in young children. The existing research base suggests that while a genetic link has been identified, specific family psychological factors (e.g., parent stress) also appear to play a significant role in the development of pediatric atopy. The function of psychological stress in the clinical expression and exacerbation of allergic diseases in young children is hypothesized to be due to neuroendocrine and immunologic systems. Specifically, stress-related activation of the sympathetic and adrenomedullary (SAM) system as well as the hypothalamic-pituitary-adrenocortical (HPA) axis from both the intrauterine environment and early childhood experiences may increase risk of childhood atopy above and beyond genetic risk. Consequently, prevention and intervention strategies aimed at reducing children's early exposure to stress and psychological difficulties in parents may prove beneficial in preventing or reducing the likelihood that their children will develop atopy

Decolonising economics and politics curricula in UK universities

© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an open access article under the Creative Commons Attribution-NonCommercial-NoDerivatives CC BY-NC-ND licence, https://creativecommons.org/licenses/by-nc-nd/4.0/This article explores initiatives to decolonise the curriculum via two specific disciplines, namely Economics and Politics, both of which have tended to marginalise the study of race, empire, and colonialism and whose canonical thinkers are overwhelming white. By providing the first comparative analysis of decolonising initiatives in these disciplines, this article: investigates the extent to which Economics and Politics curricula in UK universities have been ‘decolonised’; explores the factors which affect support for or resistance to decolonisation; and analyses the extent to which these factors share common roots in both disciplines. Our comparative method allows us to shed light on drivers of resistance that affect all disciplines alike and those that are rooted within specific disciplines. Using an audit of UK undergraduate courses and a survey of academics, we show that neither Politics nor Economics can plausibly claim to have made much progress in decolonising curricula. However, more progress has been made in Politics, and Politics staff are more informed about and less hostile to decolonising initiatives than Economics staff. We locate one of the reasons for this difference in the epistemological and ideological idiosyncrasies of the dominant neoclassical paradigm in Economics. We therefore argue that initiatives to decolonise the curriculum must take into account potential discipline-specific obstacles.Peer reviewe

Discovery of new dipper stars with K2 : a window into the inner disc region of T Tauri stars

In recent years, a new class of young stellar object (YSO) has been defined, referred to as dippers, where large transient drops in flux are observed. These dips are too large to be attributed to stellar variability, last from hours to days and can reduce the flux of a star by 10-50 per cent. This variability has been attributed to occultations by warps or accretion columns near the inner edge of circumstellar discs. Here, we present 95 dippers in the Upper Scorpius association and ρ Ophiuchus cloud complex found in K2 Campaign 2 data using supervised machine learning with a random forest classifier. We also present 30 YSOs that exhibit brightening events on the order of days, known as bursters. Not all dippers and bursters are known members, but all exhibit infrared excesses and are consistent with belonging to either of the two young star-forming regions. We find 21.0 ± 5.5 per cent of stars with discs are dippers for both regions combined. Our entire dipper sample consists only of late-type (KM) stars, but we show that biases limit dipper discovery for earlier spectral types. Using the dipper properties as a proxy, we find that the temperature at the inner disc edge is consistent with interferometric results for similar and earlier type stars

High calcium bioglass enhances differentiation and survival of endothelial progenitor cells, inducing early vascularization in critical size bone defects

Early vascularization is a prerequisite for successful bone healing and endothelial progenitor cells (EPC), seeded on appropriate biomaterials, can improve vascularization. The type of biomaterial influences EPC function with bioglass evoking a vascularizing response. In this study the influence of a composite biomaterial based on polylactic acid (PLA) and either 20 or 40% bioglass, BG20 and BG40, respectively, on the differentiation and survival of EPCs in vitro was investigated. Subsequently, the effect of the composite material on early vascularization in a rat calvarial critical size defect model with or without EPCs was evaluated. Human EPCs were cultured with β-TCP, PLA, BG20 or BG40, and seeding efficacy, cell viability, cell morphology and apoptosis were analysed in vitro. BG40 released the most calcium, and improved endothelial differentiation and vitality best. This effect was mimicked by adding an equivalent amount of calcium to the medium and was diminished in the presence of the calcium chelator, EGTA. To analyze the effect of BG40 and EPCs in vivo, a 6-mm diameter critical size calvarial defect was created in rats (n = 12). Controls (n = 6) received BG40 and the treatment group (n = 6) received BG40 seeded with 5×105 rat EPCs. Vascularization after 1 week was significantly improved when EPCs were seeded onto BG40, compared to implanting BG40 alone. This indicates that Ca2+ release improves EPC differentiation and is useful for enhanced early vascularization in critical size bone defects

Blockchain is not a silver bullet for agro-food supply chain sustainability: Insights from a coffee case study

Information sharing lies at the core of most governance interventions within agro-food commodity supply-chains, such as certification standards or direct trade relationships. However, actors have little information available to guide sustainable consumption decisions beyond simple labels. Blockchain technology can potentially alleviate the numerous sustainability problems related to agro-food commodity supply-chains by fostering traceability and transparency. Despite significant research on blockchain, there is limited understanding of the concrete barriers and benefits and potential applications of blockchain in real-world settings. Here, we present a case study of blockchain implementation in a coffee supply-chain. Our aim is to assess the potential of blockchain technology to promote sustainability in coffee supply chains through increased traceability and transparency and to identify barriers and opportunities for this. While our pilot implementation clearly illustrates certain benefits of blockchain, it also suggests that blockchain is no silver bullet for delivering agro-food supply chain sustainability. Knowledge on provenance and transparency of information on quality and sustainability can help trigger transformation of consumer behaviour, but the actual value lies in digitising the supply chain to increase efficiency and reduce costs, disputes, and fraud, while providing more insight end-to-end through product provenance and chain-of-custody information. We identify a need to understand and minimize supply chain barriers before we can reap the full benefits of digitalization and decentralization provided by blockchain technology